Bring a large pot of salted water to a boil. Add penne and cook according to package instructions. Drain penne, rinse with cold water and drain again.
Meanwhile, in a large skillet, prepare the sausage according to recipe directions. Drain.
To the turkey sausage in the skillet, add the wine and cook over medium-high heat until almost all of the wine has evaporated. Reduce heat to medium-low. In a small bowl or glass measuring cup, combine the milk and flour. Stir until smooth. Pour into the skillet with the turkey. Bring to a simmer while constantly stirring and cook until thickened. Stir in ¾ cup Parmesan cheese, 4 tablespoons parsley and the cooked penne pasta. Season with salt and pepper. Stir well.
Serve, garnishing with the remaining ¼ cup Parmesan cheese and 2 tablespoons parsley.